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  1. University of Arkansas for Medical Sciences
  2. Medicine and Meaning
  3. Our Encephalon Wrongs Us

Our Encephalon Wrongs Us

By: Matthew Zambito

Panic is accelerating as if in freefall,

a tumor on your thoughts, lesions 

on your feelings. Melancholia turns into 

dysthymia (if you’re lottery lucky) or into

a treatment-resistant depression deep

as the Mariana Trench if the Mariana Trench

got used as a drainage ditch. Tics convulse

muscles by a nervy, bedeviled compulsion. 

The holed shebang remains a mystery

of the mind with no whodunit revelation

come the last chapter. Psych-prescribed

pills popped provide effective effects plus

plenty of others on the side. Your cerebral

hemispheres keep having a hateful lovers’

quarrel over corpus callosum and require

couples counseling you can’t afford. Ideas

for brainchildren, already straightjacketed 

in a room padded with corpses, sob in-

consolably. If you’re gabbing with ghosts

you’re all the way there. You’re there,

and not, and a god, golden and bovine.

Bio

Matt Zambito is the author of The Fantastic Congress of Oddities, and two chapbooks, Guy Talk and Checks & Balances. New poems appear or are forthcoming in Freshwater Literary Journal, Braided Way, Northwest Indiana Literary Journal, and elsewhere. Originally from Niagara Falls, he now writes from Wilson, New York.

Posted by mmassirer on July 24, 2026

Filed Under: 14-poetry

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